Interrelation between Helicobacter Pylori Infection, Infantile Colic, and Irritable Bowel Syndrome in Pediatric Patients
Abdelrazak MA, Walid FE, M Abdelrahman and Mohamed Abdeltawab Mahmoud
Research Paper I Published September,2015
Journal of Medical and Biological Science Research Vol.
1 (7), pp. 85-91
ABSTRACT
To determine whether irritable bowel syndrome is associated
with Helicobacter pylori infection and infantile colic. A
retrospective case controlled study was conducted in Abha
hospital (Saudi Arabia), Abo Hariz Hospital, (Sharkia,
Egypt), and Al Hussein University Hospital (Cairo, Egypt).
450 cases of irritable bowel syndrome (IBS) that met the
Rome III criteria and 100 controls (IBS-negative), aged 7 to
17 years old, were involved in this study. Complete stool
analysis including H. pylori stool antigen test and occult
blood in addition to urea breath test, were carried out for
all participants.Of the total 450 IBS cases, 212 (47.1%) had
reported infantile colic at age 0 to 4 months compared to 7
(7.0%) in control group, and family history of IBS was
evident in case group (n = 315; 70.0%) versus control group
(n = 10; 10.0%). Furthermore, H. pylori was present
in 192 (42.7%) of IBS cases compared to only 8 (8.0%) in
control group. Our findings provide a new correlations
between childhood IBS and infantile colic as well as H.
pylori infection. Moreover, a significant association was
found between IBS and family history of IBS. 1-the
relationship between H pylori and infantile colic and
2-H pylori and adult IBS are the known while what is new is
1- Correlation between childhood IBS and infantile colic, 2-
Correlation between childhood IBS and H. pylori
infection and 3- A significant association between childhood
IBS and family history of IBS.
Key words:
Helicobacter pylori,
Rome III Criteria, Stool Antigen Test and Colic.
- Journal of Agricultural Science and Food Technology (JASFT)
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